Dr. Anupam Jana

Doctoral Research

Ph.D. (Organic Chemistry): 2015, Department of Chemistry, Indian Association for the Cultivation of Science (IACS), Kolkata.

Title: Chiral Synthons from Carbohydrates towards the Synthesis of Bioactive Natural Products.

Supervisor: Professor Subrata Ghosh, Department of Organic Chemistry, IACS-Kolkata.

Postdoctoral Research Experience

• June 2015 – January 2018: Scientific Assistant under Prof. Karol Grela, University of Warsaw, Poland.
• February 2018 – September 2020: Dr. D. S. Kothari Postdoctoral Fellow under Prof. Animesh Pramanik, University of Calcutta.
• October 2020 – April 2022: Research Associate under Dr. S.P. Swain, NIPER-Kolkata.

Research Interest

• Asymmetric Synthesis
• Green Synthesis of Biologically Important Molecules
• Total Synthesis of Natural and Pharmaceutical Products
• Design, Synthesis and Biological Evaluation of Novel Natural Product Analogues
• Organometallic Chemistry

• Junior Research Fellow (NET-CSIR): Dec. 2009, June 2010
• Graduate Aptitude Test (GATE): 2010
• Senior Research Fellow (CSIR): 2012
• D. S. Kothari Postdoctoral Fellow (UGC): 2018

Sponsored Research Grant Received

• Start-Up Research Grant from Science and Engineering Research Board (SERB), Government of India. Amount: ₹28.2 Lakhs (October 2023 – October 2025).

Research Supervision

• Postgraduate Students: 10 (4 ongoing)

1. “Protein Profiling Uncovers IGF-1R Inhibition Potential of 3-(2-Furoyl)-Indole Scaffolds in Hepatocellular Carcinoma” Efficiency Myrsing, HM Chandra Mouli, Pallaprolu Nikhil, Deepali, Abhishek Sahu, Anupam Jana,* P Ramalingam,* Future Medicinal Chemistry, 2025, 17, 513-528..
2. “Decoding the interaction of an imidazo-pyrimidine derivative with serum proteins: Spectroscopic, computational and structure-activity relationship analysis” Bishwayan Chakraborty, Asmit Santra, Debangana Tah, Koushik Goswami, Anupam Jana,* Agnishwar Girigoswami,* Debosreeta Bose* Biophysical Chemistry, 2025, 322, 107435.
3. In Silico Characterization of Indole-Substituted Densely Functionalized Pyrrole Against Breast Cancer: Integrating DFT, Molecular Docking, MD Simulations, and ADME Analysis, HM Chandra Mouli, Dharipally Harini, Nadeem Shaikh, Rahul Khemchandani, Shambhavi Shreya, Anupam Jana,* Gananadhamu Samanthula,* Journal of Molecular Structure, 2025, 1328, 141375.
4. “Method for one-pot green synthesis of pyrimidine-based fluorogenic α-amino acids for the application of protein analysis” Mohammad Zahid Hussain, Anupam Jana, Intellectual Property India Application no 202431037119 (Filled on 27^th 2024)
5. “Exploring Anticancer Potential of Furopyrano[3,4-b]indole via Graphene Oxide-Catalyzed Aqueous Synthesis” Mohammad Zahid Hussain, Efficiency Myrsing, H. M. Chandra Mouli, Krishnandu Dey, Salil Khajuria, Amit Kumar Paul, Abhishek Sahu, Anupam Jana*  ChemistrySelect, 2024, 9 (48), e202404316.
6. “Guanidine Hydrochloride (GuHCl) Catalysed Microwave-Mediated Solvent- and Metal-Free Synthesis of Pyrimido[1,2-a]benzimidazole from Aryl Aldehyde and Aryl Methyl Ketone” Rushikant Jagdale, Mohammad Zahid Hussain, Koushik Goswami, Ramalingam Peraman, Anupam Jana*, Green Chemistry, 2024, 26, 9230-9240.
7. “Unlocking therapeutic potential: exploring indole scaffolds and their structural insights as pharmacophores in designing anti-breast cancer agents”, Adithya Vinod, HM Chandra Mouli, Anupam Jana,* Ramalingam Peraman, Medicinal Chemistry Research, 2024, 33, 1100-1132.
8. “Unleashing Naphthopyranopyrimidine’s Anticancer Potential: A Deep Eutectic Solvent (DES) Study” Arindam Das,… Anupam Jana, Amit Kumar Paul, Md. Firoj Hossain* New J. Chem., 2024, 48, 7566-7578.
9. “Chromatography and Catalyst-Free Synthesis of Indole-Substituted Densely Functionalized Pyrrole” Adithya Vinod, H. M. Chandra Mouli, Poulomi Pal, Efficiency Myrsing, Vamkudoth Yaswanth Naik, Harisadhan Ghosh* and Anupam Jana*, Journal of Organic Chemistry, 2024, 89, 1407-1416.
10. “Recent advances in the palladium catalyzed synthesis of unnatural tryptophans” Koushik Goswami*, Amrita Chakraborty, Surajit Sinha* and Anupam Jana* European Journal of Organic Chemistry, 2024, 27, e202301028.
11. “Utilizing graphene oxide (GO) catalysed cascade in the synthesis of tetracyclic pyrano [3, 4‐b] indole derivatives”  Efficiency Myrsing, Aditya Vinod, H. Chandra Mouli, V. Ravichandiran, and Anupam Jana,* Asian Journal of Organic Chemistry, 2023, p.e202300126.
12. “Recent Development of Allyl-Allyl Cross-Coupling and its Application in Natural Product Synthesis” V. Ravichandiran,* Anupam Jana*  Chem. Front., 2023, 10, 267-281.
13. “Recent Advances in the Green Synthesis of Poly Functionalized Pyrroles” in Progress in Chemical and Biological Science, Lincoln University College, Malaysia; Harisadhan Ghosh,* Anupam Jana* 2023, Chapter 6, Page 60-71. (ISBN: 978-967-2819-22-6, DOI: 10.31674/book.2023pcbs).
14. “Diaryliodonium salt as oxidant in sp3 C-H activation and synthesis of quinazolin-4(3H)-ones” Nirmal Das Adhikary, Subhra Mandal, Anupam Jana, Animesh Pramanik* Results in Chemistry, 2022, 4, 100270.
15. ‘’Application of organometallic catalysts for the synthesis of o-tolyl benzonitrile, a key starting material for sartans” Anupam Jana, Ravichandiran and Sharada Prasanna Swain* New Journal of Chemistry, 2021, 45(38), pp. 17753–17771.
16. ‘’Graphene Oxide (GO) Catalysed MW-assisted One-Pot Synthesis of Densely Substituted Furan” Anupam Jana,* (as corresponding author), Nirmal Das Adhikary and Animesh Pramanik*, Green Chemistry, 2020, 22, 4304-4310.
17. “Ethyl lactate: A green solvent for olefin metathesis”, Sebastian Planer, Anupam Jana (with equal first authorship), Karol Grela*, ChemSusChem, 2019, 12, 4655-4661 (Selected as Cover Page)
18. ‘’Synthesis of Substituted β-Functionalised Styrenes by Microwave-Assisted Olefin Cross-Metathesis and Scalable Synthesis of Apremilast’’ Anupam Jana, Grzegorz Krzysztof Zieliński, Sylwia Czarnocka-Śniadała, Krzysztof Grudzień, Dominika Podwysocka, Marcin Szulc, Anna Kajetanowicz,* and Karol Grela*, ChemCatChem, 2019, 11, 5808-5813.
19. “Well-Defined Chiral Copper NHC Complex in Asymmetric Conjugated β-Borylation and One-Pot Metathesis-Asymmetric β-Borylation” Anupam Jana,* (as corresponding author), Damian Trzybiński, Krzysztof Woźniak, Karol Grela*, Chemistry – A European Journal, 2018, 24, 891-897.
20. “Forged and Fashioned for Faithfulness—Ruthenium Olefin Metathesis Catalysts Bearing Ammonium Tags” Anupam Jana, Karol Grela*, Chemical Communication, 2018, 54, 122-139. (Selected as Cover Page)
21. “Cross Metathesis’’ in “N-Heterocyclic Carbenes in Catalytic Organic Synthesis” Anupam Jana, Paweł Małecki, Karol Grela* Editor: Steven Nolan and Catherine Cazin, Science of Synthesis: Georg Thieme Verlag KG, 2017, Vol-2 Chapter 2.1.3, Pages 47-78. (ISBN: 3132414018 DOI: 10.1055/sos-SD-224-00008)
22. “Mild Functionalization of Tetraoxane Derivatives via Olefin Metathesis: Compatibility of Ruthenium Alkylidene Catalysts with Peroxides’’ Anupam Jana and Karol Grela* Organic Letters 2017, 19, 520-523.
23. “Synthesis of Selectively Substituted or Deuterated Indenes via Sequential Pd and Ru Catalysis” Anupam Jana, Kasjan Misztal, Anna Żak and Karol Grela* Journal of Organic Chemistry, 2017, 82, 4226−4234.
24. “Studies towards the synthesis of bielschowskysin. Construction of the highly functionalized bicyclo-[3.2.0]heptane segment” Anupam Jana, Sujit Mondal, Subrata Ghosh* Organic & Biomolecular Chemistry 2015, 13, 1846–59.
25. “Influence of ring fusion stereochemistry on the stereochemical outcome in photo-induced Diels-Alder reaction of fused bicycloheptenone derivatives” Subrata Ghosh*, Sritama Bose, Anupam Jana, A. Nijamudheen, Ayan Datta*. Tetrahedron 2014, 70, 9783-90.
26. “Intramolecular Diels-Alder route to angularly oxygenated hydrindanes. Synthesis of the functionalized bicylic skeleton present in galiellalactone” Md. Firoj Hossain, Ram Naresh Yadav, Sujit Mondal, Anupam Jana, Subrata Ghosh*. Tetrahedron 2013, 69, 7956-63.
27. “Stereocontrolled approach to the highly functionalized bicyclo[3.2.0] heptane core of bielschowskysin through intramolecular Cu(I)-catalyzed [2+2] photocycloaddition” Anupam Jana, Sujit Mondal, Md. Firoj Hossain, Subrata Ghosh*. Tetrahedron Letters 2012, 53, 6830-33.